FDA OKs Leucovorin For Neurological Disorder, But Not As Autism Treatment
The Trump administration has touted the synthetic vitamin B9 as a way to treat autism, but there is insufficient data to support the drug's use for it, an FDA official said. The new approval is for the treatment of cerebral folate deficiency.
The Food and Drug Administration on Tuesday announced a new approved use for the drug leucovorin, a synthetic form of vitamin B9 that the Trump administration has touted as a treatment for autism symptoms. But the new approval is not for autism 鈥 it鈥檚 for cerebral folate deficiency, a rare neurological condition characterized by low levels of vitamin B9 in the brain. (Bendix, 3/10)
On autism and Medicaid 鈥
When Meghann Mitchell first launched her autism-therapy business in 2019, she took aim at an unlikely source of profit: Indiana鈥檚 taxpayer-funded Medicaid program, the public insurance system for the poor. The bet paid off. In 2023, the state paid Mitchell鈥檚 company, Piece by Piece Autism Centers, $29 million to provide therapy to just 84 patients鈥攁bout $340,000 a child鈥攁ccording to a Wall Street Journal analysis of Medicaid billing records. (Weaver, McGinty and Wilde Mathews, 3/10)
More on the Trump administration 鈥
HHS Secretary Robert F. Kennedy Jr. was having rotator cuff surgery Tuesday, a spokesperson told MedPage Today. Kennedy plans to return to the office March 16, the spokesperson said. That person did not provide details about the reason for the procedure or which shoulder was repaired, and did not provide an update on his condition. Since his tenure at HHS began, Kennedy has frequently engaged in various physical activities publicly to promote his "Make America Healthy Again" agenda, including doing pull-ups at an airport event. (McCreary, 3/10)
The Social Security Administration鈥檚 internal watchdog is investigating a complaint that alleges a former U.S. DOGE Service employee claimed he had access to two highly sensitive agency databases and planned to share the information with his private employer 鈥 a claim that, if true, would constitute an unprecedented breach of security protocols at an agency that serves more than 70 million Americans. (Kornfield, Dwoskin and Rein, 3/10)
Dr. Lara Jones still remembers her visceral reaction to the image of Liam Ramos. It wasn鈥檛 the most famous one, of the 5-year-old boy in a blue bunny winter hat and superhero backpack with ICE officers behind him. It was one from days later, of Liam slumped in his father鈥檚 arms while both were in custody in Texas. (Rodriguez, 3/10)
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Zach Dyer reads the week鈥檚 news: The Trump administration is calling for sharp restrictions on direct-to-consumer drug ads, and for some people facing skyrocketing health insurance costs, becoming eligible for Medicare because of a new diagnosis is a terrible irony. (Cook, 3/10)
In related news on transgender health care 鈥
Though the SAVE America Act (formerly the SAVE Act) cleared the House in February, the Senate has avoided taking it up for a vote. Now, President Donald Trump has raised a series of demands that won鈥檛 make its passage any easier. Trump announced in a weekend social media post that he would 鈥渘ot sign other bills until this is passed, and not the watered down version 鈥 go for the gold,鈥 a revision that could now put anti-trans measures in the bill. (Martinez and Rummler, 3/10)
Gabrielle Jones-Radtke has lived in El Paso for nearly her entire life. She loves El Paso 鈥 its community, its culture, its recent growth 鈥 but her favorite factor is its predictability. 鈥淚f you鈥檙e young, you know, maybe that鈥檚 not the best thing,鈥 Jones-Radtke said. 鈥淏ut once you get older and have a family, predictability is everything.鈥 But a series of unpredictable circumstances is forcing her to move her family about 25 miles away to New Mexico. (Johnstone, 3/10)