Among the oldest group studied —聽women in their 80s and early 90s who are least likely to benefit from the regimen —聽the odds of receiving the more expensive brachytherapy were significantly higher at for-profit hospitals, the study found.

The research, funded by the National Cancer Institute and the Robert Wood Johnson Foundation, was published Monday in the May issue of the journal Surgery.

“We wanted to see whether for-profit hospitals, which arguably have a greater incentive to provide returns to their shareholders, would be more likely to adopt a higher-reimbursement therapy than a nonprofit hospital — and that’s exactly what we found,” said Dr. Cary P. Gross, a professor of medicine at Yale University School of Medicine and the paper’s senior author.

“This reinforces the idea that reimbursement is a significant driver of the adoption of new cancer therapies, which is a shame,”聽Gross said. “Evidence should be the main driver.”

Brachytherapy is a newer type of radiation therapy for breast cancer that involves implanting a radiation source into the lumpectomy cavity of the breast. It is a shorter course of treatment than standard radiation and can be completed in one week instead of four to six weeks. But it costs about twice as much as the standard treatment, and and whether its harms may outweigh its benefits.

The retrospective study looked at the care 35,118 women between聽 the ages of 66 and 94 covered by the government’s Medicare program received after breast-conserving surgery for breast cancer in 2008 and 2009. The women had surgery at 2,684 hospitals in the United States; only 8 percent were treated at for-profit hospitals.

Among the patients who underwent radiation treatment, 15.2 percent received brachytherapy at nonprofit hospitals, compared with 20 percent of those treated at for-profit hospitals.

There was no association between the hospital’s status and overall radiation treatment for women aged 66 to 79, although women in that age group who received radiation at a for-profit hospital were also more likely to get brachytherapy.

Among women aged 80 to 94, who benefit least from radiation therapy because they are unlikely to live long enough for their cancer to recur, 58.9 percent received radiation at for-profit hospitals, compared with 53.9 percent at nonprofits,聽while 12.4 percent received brachytherapy at for-profit hospitals, compared with 8 percent at nonprofits.

For these patients, “who may not have gotten radiation to begin with,聽 brachytherapy is driving an overall increase in the use of radiation,” Gross suggested.

The study聽notes that a driving factor in using brachytherapy is the attempt to enhance convenience and tolerability.聽“However, it is unclear why patient preferences for radiation modality would vary with hospital ownership,”聽it said.

Gross said the take-home message for patients is that treatment recommendations vary from provider to provider, and they should always get a second opinion. Both physicians and members of the general public tend to become “enamored” with new treatment options, he said, even when the evidence is limited or lacking.

“Don’t just ask the doctor which type of treatment you should get,” he said.聽 “Ask the doctor, 鈥榃hat happens if I don’t get this treatment? How does this affect the outcome?’”

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