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Wednesday, May 29 2024

Full Issue

Ancient Egyptians Pioneered Cancer Treatments, Scrutiny Of Skulls Shows

In other cancer research, a Merus-Keytruda combination treatment is showing promise for patients with head and neck cancer, and a new transplant technique for people with lung cancer has a 100% success rate.

Ancient Egyptian doctors were the first to explore and treat cancer, according to scientists who examined two skulls with tumors and found evidence they had been operated on. The older of the two, both discovered in Giza, Egypt, belonged to a man between the ages of 30 and 35 who died more than 4,000 years ago. While the cause of death remains uncertain, the man鈥檚 skull and jaw had over 30 cancerous bone lesions. Microscopic analysis of the bone and micro-CT scans revealed cut marks made by a sharp, metal instrument, likely a knife, in the areas around the tumors. (Woodward, 5/29)

More cancer news 鈥

Merus said Tuesday that the combination of its experimental drug petosemtamab with the checkpoint inhibitor Keytruda shrank tumors in 62% of patients with head and neck cancer, according to an interim analysis of an ongoing mid-stage clinical trial. (Feuerstein, 5/28)

For decades, double lung transplants were not considered a viable option for treating lung cancer. 鈥淚t had been done, but it had always failed,鈥 said Ankit Bharat, chief of thoracic surgery at Northwestern Medicine. 鈥淲hen you took out the lungs, the cancer cells would spread to the rest of the body, and it would come back a matter of months after the transplant.鈥 (Kalra, 5/28)

Patients who live farther away from a designated comprehensive cancer center may be more likely to receive a late-stage diagnosis, according to an analysis of medical records from researchers at Baltimore-based John Hopkins Medicine. Researchers analyzed records from more than 94,000 cancer patients to assess how proximity to a National Cancer Institute-designated comprehensive cancer center, insurance status and other social determinants of health affect the odds of receiving an early- or late-stage cancer diagnosis. The team evaluated data from patients in the Johns Hopkins Hospital cancer registry who received a diagnosis, cancer treatment or both from 2010 to 2019.聽(Carbajal, 5/28)

A low-fat diet has been associated with a lower risk of lung cancer in a cohort of people in the United States. Researchers from China analyzed data from a cohort of over 98,000 people taking part in a U.S.-based cancer study, and found a 24% lower risk of lung cancer in people who had the lowest amount of fat in their diets. This reduction was even more pronounced, standing at a 29% reduced risk in smokers who had the lowest-fat diets. (Flynn, 5/28)

Gwendolyn Jackson was financially sound before her cervical cancer diagnosis鈥攕he was gainfully employed, insured and secure in a home of her own. But now, the 53-year-old has tens of thousands of dollars of medical debt. Chemotherapy drained her energy and she suffered other health problems, including a stroke. She lost her housing-coordinator job because of the physical toll. An eviction notice showed up on Jackson鈥檚 door, and her truck was repossessed. 鈥淥ne morning, I woke up and I was a top case manager,鈥 said Jackson, who lives in Houston. 鈥淭hen I was losing everything.鈥 (Abbott and Loftus, 5/28)

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