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Morning Briefing

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Monday, Jun 1 2015

Full Issue

Cancer Drug Manufacturers Criticized For Escalating Costs, Shortages

A prominent cancer specialist called out pharmaceutical companies at a speech before the American Society of Clinical Oncology, saying “cancer-drug prices are not related to the value of the drug.” Other doctors are frustrated by production delays that have left the cancer drug, BCG, in short supply. Shortages of other painkillers and antibiotics have also hamstrung hospitals.

In a sign of growing frustration with rising drug prices, a prominent cancer specialist on Sunday sharply criticized the costs of new cancer treatments in a high-profile speech at one of the largest annual medical meetings in the U.S. “These drugs cost too much,” Leonard Saltz, chief of gastrointestinal oncology at Memorial Sloan Kettering Cancer Center, said in a speech heard by thousands of doctors here for the annual meeting of the American Society of Clinical Oncology. (Walker, 6/1)

Robin Miller, a 62-year-old oncologist in Atlanta with bladder cancer, was scheduled to receive a potentially lifesaving drug in December. But her doctor’s office called shortly before the appointment to say: “Sorry, we don’t have any. We can’t give it to you,” according to Dr. Miller. The disruption was due to a global shortage of the drug, BCG, which arose after manufacturing problems at two of the few global suppliers. Without the drug, Dr. Miller feared her cancer would come back and she would have to have her bladder removed, a step she called “barbaric.” (Loftus, 5/31)

Studies show that "promising" new immune-therapy drugs can extend the lives of patients with common forms of cancer, like lung and skin. The medications are costly with strong side effects, and only work on a minority of patients. So researchers say it's critical to develop screenings to determine who will benefit from the treatment -

A new drug that unleashes the body’s immune system to attack tumors can prolong the lives of people with the most common form of lung cancer, doctors reported on Friday, the latest example of the significant results being achieved by this new class of medicines. In a separate study, researchers said they had found that a particular genetic signature in the tumor can help predict which patients could benefit from the immune-boosting drugs. The finding could potentially extend use of these drugs to some patients with colorectal cancer, prostate cancer and other tumors that have seemed almost impervious to the new drugs. (Pollack, 5/29)

For the first time, a major study shows that a drug targeting the body’s disease-fighting immune system may improve survival for the most common form of lung cancer. These newer kinds of drugs have transformed treatment of melanoma, the deadliest kind of skin cancer. Studies presented at a conference Friday suggest these “immune therapies” can play a broader role in more common cancers, including lung, liver, colon and head and neck. (Tanner, 5/29)

New drugs that boost the immune system’s ability to fight tumors may be one of the greatest medical advances in years, cancer doctors say, pulling some patients from death’s door and keeping them in remission for years. But the truth is that this happens for only a minority of patients. Now, doctors say, there is a new imperative to develop a test that will identify in advance which patients will benefit, sparing others the cost and possible side effects.n (Pollack, 5/31)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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