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Morning Briefing

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Wednesday, Feb 5 2025

Full Issue

Good News For Parkinson's Patients: FDA OKs New Wearable Treatment

MedPage Today reports on the infusion device, aimed at treating motor fluctuations in adults with advanced Parkinson's disease. Also in public health news: hopes are dimmed for GLP-1 drugs' ability to treat Parkinson's; a new blood test may detect colon cancer with 80% accuracy; and more.

The FDA approved an apomorphine hydrochloride infusion device (Onapgo) to treat motor fluctuations in adults with advanced Parkinson's disease, Supernus Pharmaceuticals announced on Tuesday. The wearable device is the first subcutaneous apomorphine infusion device for Parkinson's and provides continuous treatment during the day, Supernus noted. (George, 2/4)

The idea was so tantalizing. Drugs in the GLP-1 class, which includes Wegovy and Ozempic, have proved miraculous in treating weight loss and other diseases. And some researchers hoped that the drugs could also help with some of the most difficult diseases to treat 鈥 those of the brain, like Parkinson鈥檚. But now, at least for Parkinson鈥檚, that hope seems dimmed. A rigorous study that randomly assigned Parkinson鈥檚 patients to take exenatide, a relative of Ozempic, showed absolutely no benefit or slowing of the course of the degenerative disease after 96 weeks. (Kolata, 2/4)

More health and wellness news 鈥

A new blood test was found to detect colon cancer with more than 80% accuracy 鈥 and to rule it out for 90% of healthy people. The results were presented at the 2025 American Society of Clinical Oncology Gastrointestinal Cancers Symposium held in San Francisco late last month. They were also published in the Journal of Clinical Oncology. (Rudy, 2/4)

Since the 1990s, a race-based method for assessing kidney function placed many Black patients lower on the transplant waitlist. However, thousands of these patients were moved up the list in recent years when a widely used lab test was found to calculate results differently for Black patients. "We have a long history in this country of actually biases against certain transplant candidates, in particular African Americans, because of the way that we calculate how bad the kidney function is," Dr. Edmund Pribitkin, a professor at Thomas Jefferson University, said. (Smith and Louallen, 2/4)

Your parents may be right: Get some sleep and you鈥檒l feel better in the morning, according to new research. 鈥淥ur study suggests that people鈥檚 mental health and wellbeing could fluctuate over time of day,鈥 said lead study author Dr. Feifei Bu, principal research fellow in statistics and epidemiology at University College London, in an email. 鈥淥n average, people seem to feel best early in the day and worst late at night.鈥 (Holcombe, 2/4)

麻豆女优 Health News: Listen To The Latest '麻豆女优 Health News Minute'

Renu Rayasam delivers this week鈥檚 news: There are still no proven therapies for long covid despite more than $1 billion in federal funding, and some hospitals are assigning dogs to work alongside medical staff in hospitals to help them cope with burnout and stress. (2/4)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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