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Thursday, Oct 27 2016

Full Issue

HIV's Patient Zero Mythology Debunked

New genomic sequencing research shows that the virus has been in America a lot longer than previously thought.

In the tortuous mythology of the AIDS epidemic, one legend never seems to die: Patient Zero, a.k.a. Ga茅tan Dugas, a globe-trotting, sexually insatiable French Canadian flight attendant who supposedly picked up H.I.V. in Haiti or Africa and spread it to dozens, even hundreds, of men before his death in 1984. Mr. Dugas was once blamed for setting off the entire American AIDS epidemic, which traumatized the nation in the 1980s and has since killed more than 500,000 Americans. The New York Post even described him with the headline 鈥淭he Man Who Gave Us AIDS.鈥 (McNeil, 10/26)

In a study published Wednesday in the journal Nature, researchers used genomic聽sequencing of blood samples from that era to go back in time and reconstruct聽the 鈥渇amily tree鈥 of the聽virus in unprecedented detail. The findings are stunning, debunking many popular beliefs about the virus's聽origins and spread and filling in holes about how it made its way to the United States. (Cha, 10/26)

Instead, the researchers聽report that Dugas聽was one of thousands of people who were infected with the human immunodeficiency聽virus by聽the late 1970s, years聽before it聽was officially recognized by the medical community in 1981. The genetic analysis also reveals the path taken by聽the most common strain of the virus after聽it聽traveled from聽the Caribbean to the United States.聽Upon arriving聽in New York City聽around 1970,聽it circulated and diversified for about five years聽before聽being聽dispersed across the country. (Netburn, 10/26)

"The virus got to New York City pretty darn early," says evolutionary biologist Michael Worobey, who led the study. "It was really under the radar for a decade or so." (Doucleff, 10/26)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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