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Wednesday, Feb 12 2025

Full Issue

Lung Fridge Innovation Triples Surgeons' Transplant Window

Prior to the fridge, lungs would be kept on ice, which could damage them. The fridge allows for more flexibility in scheduling, which in turn can lead to fewer mistakes. Other promising news is on drug approvals for genetic disorders, weight loss surgery for liver disease, and more.

The lungs that Dr. Ankit Bharat took out of Tadd Crosslin, a 49-year-old father of twins, were marred with billions of cancer cells. They were 鈥減erhaps the most diseased that we鈥檝e ever seen,鈥 said Bharat, a thoracic surgeon and director of Northwestern Medicine鈥檚 Canning Thoracic Institute. A technology the institute adopted just months ago was a game changer for Crosslin, whose lungs were fused so tightly to his chest cavity that doctors needed extra time to delicately remove them. (Breen, 2/11)

The Food and Drug Administration (FDA) approved a new drug to treat a disorder causing the growth of noncancerous tumors on nerves throughout the body.聽The federal agency said on Tuesday it greenlighted聽SpringWorks Therapeutics鈥檚 drug Gomekli for patients dealing with neurofibromatosis type 1 (NF1) 鈥渨ho have symptomatic plexiform neurofibromas (PN) not amenable to complete resection.鈥澛(Timotija, 2/11)

Until recently, doctors could only hope to intervene by suggesting diet and lifestyle changes, or by helping patients manage related conditions like diabetes or high cholesterol. But those efforts often haven鈥檛 been enough. Now a promising new study shows that weight-loss surgery could reduce the chances of severe complications, even in some patients with cirrhosis. (Agrawal, 2/11)

Today the Coalition for Epidemic Preparedness Innovations (CEPI) announced an award of $5 million funding award to Ethris, a German biotechnology firm working on next-generation RNA vaccines.聽The award will help Ethris develop spray-dried RNA vaccines that remain stable at room temperature and are suitable for nasal delivery, CEPI said in a press release. (Soucheray, 2/11)

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