Morning Briefing
Summaries of health policy coverage from major news organizations
Paxlovid Cuts Death Rates In Half When Taken On Day Zero Or 1
Starting the antiviral drug nirmatrelvir-ritonavir (Paxlovid) 0 or 1 day after COVID-19 symptom onset halved 28-day all-cause death and hospitalization rates compared with waiting 2 or more days, University of Hong Kong researchers report in Nature Communications. (Van Beusekom, 12/19)
Researchers have comprehensively identified the allosteric control sites found in the protein KRAS.聽These are highly sought after targets for drug development, representing secret vulnerabilities which can be exploited to control the effects of one of the most important causes of cancer. (Center for Genomic Regulation, 12/18)
The U.S. Food and Drug Administration on Friday approved Astellas Pharma's (4503.T) Padcev in combination with Merck's (MRK.N) Keytruda for a type of bladder cancer. In April, FDA had granted accelerated approval to this combination for treating patients suffering from the disease that are ineligible for chemotherapy with the commonly used cancer drug, cisplatin. (12/15)
The U.S. Food and Drug Administration (FDA) on Friday approved Arcutis Biotherapeutics' (ARQT.O) drug for treating a skin condition called seborrheic dermatitis in individuals nine years of age and older. Shares of Arcutis jumped 20% in extended trade to $2.94. (Jain, 12/15)
Bristol Myers Squibb said its study that evaluated treating metastatic colorectal cancer through a combination of nivolumab and relatlimab will be discontinued. The global biopharmaceutical company on Friday said the decision regarding the Phase 3 Relativity-123 trial comes after receiving a planned analysis conducted by an independent data-monitoring committee. (Ojea, 12/15)
