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Researchers identified a mechanism for why some people will itch from an allergen or mosquito bite exposure, while others will not in a new study, and showed this pathway can be targeted to prevent allergic responses in preclinical models. (Mass General Brigham, 9/4)

Some per- and polyfluoroalkyl substances (PFAS) are poorly degradable and are also known as 'forever chemicals'. They adversely affect health and can lead to liver damage, obesity, hormonal disorders, and cancer. A research team has investigated the effects of PFAS on the brain. (Helmholtz Centre for Environmental Research - UFZ, 9/4)

In June 2019, a patient presented with persistent fever and multiple organ dysfunction after a tick bite at a wetland park in Inner Mongolia. Next-generation sequencing in this patient revealed an infection with a previously unknown orthonairovirus, which we designated Wetland virus (WELV). (Zhang et al, 9/4)

Targeting pituitary adenylate cyclase–activating polypeptide (PACAP) is a new avenue for treating migraine. The efficacy and safety of intravenous Lu AG09222, a humanized monoclonal antibody directed against the PACAP ligand, for migraine prevention are unclear. (Ashina et al, 9/4)