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New research from Argentina suggests a potential link between a commonly used herbicide and antimicrobial resistance (AMR). In a study published this week in Frontiers in Microbiology, a team led by researchers from the University of Buenos Aires assessed resistance to glyphosate in environmental bacteria from soil and bacteria collected from Argentinian hospitals. (Dall, 3/25)

Setidegrasib showed promising efficacy in patients with previously treated advanced KRAS G12D-mutated pancreatic ductal adenocarcinoma (PDAC) or non-small cell lung cancer (NSCLC), results from a phase I trial suggested. (Bassett, 3/25)

An intervention designed to promote high fluid intake failed to reduce symptomatic stone recurrence in patients with a history of urinary stone disease, a randomized trial showed. (Bassett, 3/23)

A hormone traditionally used to treat bone loss may hold the key to stopping chronic back pain at its source, according to a new study. Chronic back pain is often linked to the deterioration of spinal discs and vertebral end plates, which are the thin layers of tissue separating the discs from the vertebrae, according to medical sources. (Quill, 3/25)

The concept of transesophageal echocardiography (TEE) guidance during CPR hit a wall when tested for the first time in a randomized trial. For patients who were in a prolonged out-of-hospital cardiac arrest (OHCA) and very sick upon arrival to an emergency department (ED), subsequent performance of TEE-guided CPR with compression site adjustment was no better than standard CPR. (Lou, 3/23)