Morning Briefing
Summaries of health policy coverage from major news organizations
Researchers Look For Key To Cures In 'Exceptional Responders'
In 2010, [Grace] Silva was diagnosed with anaplastic thyroid cancer, an aggressive and rapidly fatal disease with no effective treatment. Despite surgery, chemotherapy and radiation, the cancer spread to her lungs. As a last resort, she enrolled in a small clinical trial the following year. ... Silva got a drug called everolimus, approved for advanced kidney cancer and some types of breast and pancreatic cancer. The other patients died, but Silva’s tumors virtually vanished, to the astonishment of her doctors. Such inexplicable reversals have always existed in medicine, but until recently, outliers such as Silva remained little more than hopeful anecdotes. That could be changing. (Dennis, 6/13)
With a family history of breast cancer, Marcie Jacobs decided in June 2001 that an MRI screening was her best preventive option. As is common with MRIs, Jacobs was injected beforehand with a contrast agent, a drug that helps sharpen the resulting images. But after a few of these treatments, she began noticing some strange cognitive effects. Jacobs began missing meetings. Over the next several years she had additional MRIs. The math skills that were crucial to her job as finance manager started deteriorating, she said. Jacobs eventually wound up on disability. She stopped worrying about cancer – and started worrying about imaging drugs. (Gerth, 6/11)