Scientists Zero In On When Cells Turn Cancerous, Devise Process To Reverse It

In a trial on colon cancer cells, researchers found that at the moment of critical transition — when cancer and normal cells coexist — they were able to flip the molecular switch that allowed normal cells to recover. Also, an early phase trial on a cancer vaccine is showing promise.

Scientists have discovered a molecular switch that can reverse cancer—turning cancer cells back into their healthy counterparts. The revelation by researchers from the Korea Advanced Institute of Science & Technology (KAIST) in Daejeon, South Korea, could lead to new cancer treatments. (Randall, 2/6)

Nine patients with advanced kidney cancer who received an experimental vaccine tailored to their tumors’ specific mutations mounted an immune response to their disease and remained cancer-free for three years, an early-phase clinical trial has shown. (Cooney, 2/5)

Technology and hospital-at-home programs are paving the way for in-home treatments to be the new frontier in cancer care — if reimbursement and other challenges can be worked out. Mayo Clinic, Huntsman Cancer Institute, Mount Sinai and Memorial Sloan Kettering Cancer Center are among the providers leveraging acute care at-home programs and telehealth to treat certain patients outside of traditional care settings as the number of cancer diagnoses in the U.S. climbs. But patient safety, regulatory and reimbursement challenges are obstacles to expanding in-home cancer care. (Eastabrook, 2/6)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.

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