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Morning Briefing

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Monday, Feb 10 2025

Full Issue

Second Person Living With Pig Kidney Is Off Dialysis And Out Of Hospital

A 66-year-old New Hampshire man received the kidney as part of a small pilot study at Mass General Brigham. United Therapeutics, another developer of gene-edited pig organs, just won FDA approval for the world鈥檚 first clinical trial. Meanwhile, studies suggest a link between sleeping pills and the risk of dementia.

A New Hampshire man fought for the chance at a pig kidney transplant, spending months getting into good enough shape to be part of a small pilot study of a highly experimental treatment. His effort paid off: Tim Andrews, 66, is only the second person known to be living with a pig kidney. Andrews is free from dialysis, Massachusetts General Hospital announced Friday, and recovering so well from the Jan. 25 transplant that he left the hospital a week later. (Neergaard, 2/7)

More science and research news 鈥

Nan Bishko Iwasaki, 81, a retired commercial artist who lives in Redondo Beach, California, has been taking a variety of sleeping pills for 22 years. She worries about their side effects, especially the possibility they might raise her risk of dementia, but 鈥淚 can鈥檛 sleep when I try to stop taking them,鈥 she says. Her concern may be warranted, experts say. A number of studies suggest an association between the risk of dementia and sleep aids, both prescription and over-the-counter, although existing research has not proved a specific cause-and-effect, according to experts. (Cimons, 2/9)

Parents and doctors often think about children鈥檚 sleep all wrong, says psychologist Jessica Lunsford-Avery. Instead of focusing on quantity of hours, they should pay more attention to quality of rest. ... Lunsford-Avery鈥檚 most recent study links slow-wave differences in children with attention-deficit/hyperactivity disorder to daytime 鈥渆xecutive functioning,鈥 which includes problem-solving, planning ahead and controlling impulsivity. But her work has ramifications for others battling insomnia, including people struggling with anxiety and depression. (Ellison, 2/7)

The HOPE trial made another case for extending the therapeutic window for IV thrombolysis in acute ischemic stroke, potentially widening the pool of people eligible for therapy. (Lou, 2/8)

The FDA has approved aztreonam and avibactam (Emblaveo) in combination with metronidazole for adults who have limited or no alternative options for the treatment of complicated intra-abdominal infections, AbbVie announced Friday. ... According to the company, the product is the first and only fixed-dose, intravenous, monobactam/beta-lactamase inhibitor combination antibiotic to receive FDA approval. (Bassett, 2/7)

Many people undergo a juice cleanse in an effort to detoxify the body and improve health, but new research suggests they do more harm than good. Researchers from Northwestern and San Raffaele universities found a diet of only vegetable and fruit juice, even for just three days, can lead to shifts in gut and oral bacteria linked to inflammation and cognitive decline.聽The study, published in the 鈥淣utrients鈥 journal,聽looked at three groups of healthy adults following different diets. (Delandro, 2/7)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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