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Tuesday, Apr 25 2017

Full Issue

These Patients Weren't Expected To Survive, But In Doing So They Changed The Trajectory Of Medicine

Stat talks with Dr. Brian J. Druker and his patients who were some of the first to be shifted away from a scorched-earth treatment of cancer to precision medicine. In other public health news: mapping the brain's neurons, the dangers of nursery products, long-term birth control, genital mutilation and more.

This is a story of survivors 鈥 of patients who were expected to die more than two decades ago but didn鈥檛. It was the summer of 1998, and Dr. Brian J. Druker was a few months into Phase 1, first-in-human trials of a promising compound that would later be known as Gleevec. Druker, a researcher at Oregon Health and Science University, knew from lab studies that the drug could disable a gene that controls certain leukemia cells, while leaving healthy cells intact. But he didn鈥檛 have answers to a lot of other questions, including what dose would be beneficial. (Tedeschi, 4/25)

Zoran Popovi膰 knows a thing or two about video games. A computer science professor at the University of Washington, Dr. Popovi膰 has worked on software algorithms that make computer-controlled characters move realistically in games like the science-fiction shooter 鈥淒estiny.鈥 But while those games are entertainment designed to grab players by their adrenal glands, Dr. Popovi膰鈥檚 latest creation asks players to trace lines over fuzzy images with a computer mouse. It has a slow pace with dreamy music that sounds like the ambient soundtrack inside a New Age bookstore.The point? To advance neuroscience. (Wingfield, 4/24)

Baby carriers, cribs, strollers, high chairs, changing tables, bath seats 鈥 these ordinary nursery products result in an average of 66,000 injuries a year requiring trips to the emergency room for young children.聽Using data from the National Electronic Injury Surveillance System, researchers estimate that from 1991 to 2011, there were 1,391,844 injuries among children under 3 that were serious enough to be treated in a hospital. (Bakalar, 4/24)

For many women this college graduation season, the primary reason to see a doctor soon after graduation may be to get birth control.聽They may want to stick with whatever they鈥檝e been using, whether that鈥檚 the pill or the patch or the vaginal ring. Or they may want to consider a broad menu of options that vary with regard to ease of use, side effects and duration of protection. (Adams, 4/24)

It was the summer of 1990.Mariya Taher was 7 years old, vacationing in India with her family, when one day her mother took her to a run-down apartment building without explaining why. She remembers climbing some stairs, opening a door and seeing older women in a room. There was laughter, and the place seemed cheerful. But then came the betrayal. (Baldas, 4/22)

Getting diagnosed with a life-threatening illness can feel like flying along at 36,000 feet and suddenly you鈥檙e plummeting toward the ground with the plane鈥檚 engine on fire...聽No matter how dire the diagnosis, you can regain control and pilot your life鈥檚 flight to a smooth landing. That鈥檚 the message from longtime palliative care physician Dr. Steven Pantilat, a University of California, San Francisco, School of Medicine professor who believes there are better ways to confront and cope with serious illness, whether it鈥檚 cancer, lung disease, heart failure, Alzheimer鈥檚 or other life-changing maladies. (Buck, 4/24)

For reasons both economic and cultural, Hispanic men are loath to interact with the health system. Women across all races are more likely to seek care than men. But the gender gap in the Hispanic community is especially troubling to health care providers. Studies show that Latino men are much less likely than Latinas to get treatment. That is true even though Hispanic men are more likely than non-Hispanic whites to be obese, have diabetes or have high blood pressure. (Anft, 4/25)

In Europe, cold caps, or cooling caps, have been used sporadically since the 1970s and are now widely available. ... In February, the Journal of the American Medical Association (JAMA) reported about two new studies, one from the University of California, San Francisco, and the other from Baylor College of Medicine in Houston. In both trials, more than half of the women who received chemotherapy for early-stage breast cancer and wore cooling caps were able to keep most of their hair. (Ridderbusch, 4/24)

All parents wonder when to have 鈥渢he talk鈥 with their child.But for parents of a child with a disability, 鈥渢he talk鈥 has an entirely different meaning: explaining the child鈥檚 diagnosis to him or her. In both cases, how much to say, and how to say it, will depend on the child鈥檚 unique abilities, and on the relationship with their parents. (Jaskiewicz, 4/25)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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