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The New England Journal of Medicine is arguably the best-known and most venerated medical journal in the world. Studies featured in its pages are cited more often, on average, than those of any of its peers. And the careers of young researchers can take off if their work is deemed worthy of appearing in it. But following a series of well-publicized feuds with prominent medical researchers and former editors of the journal, some are questioning whether the publication is slipping in relevancy and reputation. The journal and its top editor, critics say, have resisted correcting errors and lag behind others in an industrywide push for more openness in research. And dissent has been dismissed with a paternalistic arrogance, they say. (Ornstein, 4/5)