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A new blood test that detects a hallmark of Alzheimer's is poised to change the way doctors diagnose and treat the disease. The test, the first of its kind to be cleared by the Food and Drug Administration, is for people 55 and older who already have memory problems or other signs and symptoms of Alzheimer's. (Hamilton, 5/21)

People diagnosed with herpes simplex virus type 1 (HSV-1), the virus responsible for cold sores, were more likely to have a subsequent Alzheimer's disease diagnosis, an analysis of U.S. commercial insurance claims suggested. (George, 5/21)

Middle-aged and older adults who experience pain are more likely to have had worsening symptoms of depression up to eight years before the pain began, according to a new study. (University College London, 5/20)

Racial and ethnic differences in the severity, prognosis, and mortality of multiple sclerosis (MS) have been the focus of intensifying research over the last decade, and emerging evidence suggests that Black and Hispanic MS patients have more disability risk than white patients. (Smyth, 5/21)

A large observational study provides evidence that antibiotics provide no benefit for patients hospitalized with nonsevere COVID-19. (Dall, 5/21)

Investigators analyzing data on almost 2 million women participating in 17 studies observed a slight and transient increase in the length of menstruation after they received a COVID-19 vaccine, according to a study published late last week in PLOS One. The authors said the study offers clarity on the topic. "Given the extensive reporting by the media on the topic, a continued lack of clarity can fuel further vaccine hesitancy, not just for COVID-19 vaccines but also more broadly with serious implication," they wrote. (Soucheray, 5/19)

Women with rheumatoid arthritis, lupus or systemic sclerosis were more than twice as likely to suffer a cardiovascular disease-related death compared to men with the same conditions between 1999 and 2020, according to a study published May 5 in Circulation: Cardiovascular Quality and Outcomes. “There is a common perception that people with immune-mediated inflammatory diseases primarily die from infections or kidney disease,” Issam Motairek, MD, an internal medicine resident at Cleveland Clinic and the lead study author, said in a May 6 news release from the American Heart Association. (Gregerson, 5/20)

Patients with thyrotoxicosis who developed thyroid storm died at nearly double the rate as those without thyroid storm, according to an analysis using National Inpatient Sample (NIS) data from 2016 to 2021. Among over 186,000 patients with thyrotoxicosis, age-adjusted mortality per 100,000 hospitalizations was 6,825 for patients who had thyroid storm compared with 3,601 for patients without, found Shehar Bano, MD, of AdventHealth Sebring in Florida. (Monaco, 5/18)

Incorporating chest CT imaging and respiratory symptoms into the chronic obstructive pulmonary disease (COPD) diagnostic schema improved identification of individuals with poor respiratory outcomes, two longitudinal cohorts showed. The schema newly classified 15.4% of persons without airflow obstruction as having COPD by minor diagnostic category, Surya P. Bhatt, MD, MSPH, of the University of Alabama at Birmingham, reported at the American Thoracic Society annual meeting in San Francisco. (Phend, 5/18)